IJIMS.2019.102

Type of Article: Original Research

Volume 6; Issue 1: 2019

Page No.: 765-768

DOI: 10.16965/ijims.2019.102

EVALUATION OF PULMONARY HYPERTENSION IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE

G. Peter Praveen Herald 1, H Krishna Murthy *2.

1 Assistant Professor, Department of Pulmonary Medicine, Viswabharthi Medical college, Penchikalapadu, Kurnool, Andhra Pradesh, India.

*2 Head of the Department of Pulmonary Medicine, Viswabharthi Medical college, Penchikalapadu, Kurnool, Andhra Pradesh, India.

Corresponding Author: Dr. H Krishna Murthy,  Head of the Department of Pulmonary Medicine, Viswabharthi Medical college, Penchikalapadu, Kurnool, Andhra Pradesh. 9440557565. E-Mail: drkrishhmurthy56@gmail.com, peterpraveenherald@gmail.com

Abstract:

Introduction:  The early detection and treatment of pulmonary hypertension in chronic obstructive pulmonary disease (COPD) becomes important to prevent right heart failure. We aimed to pulmonary hypertension in COPD patients by non-invasive methods.

Materials and Methods: After Ethical committee clearance, the purpose of the study was explained to the patient and obtained informed consent from 105 Clinically diagnosed as COPD were included and ECG, Chest X-Ray, 2-D Echocardiography pulmonary hypertension is evaluated.

Results: Of 105 COPD patients, 96 had PH. Prevalence of pulmonary hypertension in COPD patients were 54 (51.43%):  9 (25.71%) of mild COPD patients, 16 (45.71%) of moderate COPD and 29 (82.85%) of severe COPD.

Conclusion: the chest radiography electrocardiography and 2 D-Echocardiography are the best clinical assessment and non-invasive investigations for the screening for pulmonary hypertension and subsequent development of cor pulmonale.

Key words: Chronic Obstructive Pulmonary Disease, Cor Pulmonale, Magnetic Resonance Imaging, Pulmonary Hypertension.

REFERENCES

  1. John R Reilly, Jr, Edwin K Silverman, Steven D Shapiro, Chronic Obstructive Pulmonary Disease, Chapter 254, Harrison’s Principles of Internal Medicine, Fauci, Braunwald, Kasper, Hauser, Longo, Jameson, Loscalzo, 17th edition, Page 1635.
  2. Guidelines for diagnosis and treatment of Pulmonary Hypertension by European society of Cardiology and European respiratory society. European Heart Journal .2009; 30:2493–537.
  3. Michel Migueres. Pulsed Doppler echocardiography in diagnosis of Pulmonary Hypertension in COPD, 1990; 98:280-5.
  4. Global Strategy for the Diagnosis, Management & Prevention of Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine.2007;176:532-55.
  5. Shruthi Reddy, Rajender, Nithin Reddy. Prevalence of Pulmonary Hypertension in COPD Patients: A Retrospective Observational Study.  Int J Intg Med Sci 2016;3(5):285-9.
  6. Weitzenblum E, Hirth C, Ducolone A, Mirhom R, Rasaholinjanahary J, Ehrhart M. Prognostic value of pulmonary artery pressure In chronic COPD: Thorax. 1981;36:752-8.
  7. Weitzenblum E, Sautegeau A, Ehrhart M, Mammosser M, Hirth C, Roegel E. long term course of pulmonary artery pressure In chronic COPD. Am Rev Respir Dis. 1984;130:993-8.
  8. Burrows B, Kettel LJ, Niden AH, Rabinowitz M, Diener CF. Patterns of cardiovascular dysfunction in COPD. N Engl J Med. 1972;286:912-8.
  9. Fishman AP. State of the art: Chronic cor pulmonale. Am Rev Respir Dis. 1976;114:775-94.
  10. Pietra G. Pathology of the pulmonary vasculature and heart. In; Cherniack N, editor. COPD. Philadelphia: WB Saunders; 1996;21-6.
  11. Thabut G, Dauriat G, Stern JB, Logeart D, Lévy A, Marrash-Chahla R, et al: Pulmonary haemodynamics in advanced COPD candidates for lung volume reduction surgery or lung transplantation. Chest. 2005;127:1531-6.
  12. Weitzenblum E, Hirth C, Ducolone A, Mirhom R, Rasaholinjanahary J, Ehrhart M. Prognostic value of pulmonary artery pressure In chronic COPD: Thorax. 1981;36:752-8.
  13. Weitzenblum E, Sautegeau A, Ehrhart M, Mammosser M, Hirth C, Roegel E. long term course of pulmonary artery pressure In chronic COPD. Am Rev Respir Dis .1984;130:993-8.
  14. Thabut G, Dauriat G, Stern JB, Logeart D, Lévy A, Marrash-Chahla R, et al: Pulmonary haemodynamics in advanced COPD candidates for lung volume reduction surgery or lung transplantation. Chest.2005;127:1531-6.
  15. Weitzenblum E, Sautegeau A, Ehrhart M, Mammosser M, Pelletier A. Long-term oxygen therapy can reverse the progression of pulmonary hypertension in patients with chronic obstructive pulmonary disease. Am Rev Respir Dis.1985;131:493-8.
  16. Kessler R, Faller M, Weitzenblum E, Chaouat A, Aykut A, Ducolone´A, et al. “Natural history” of pulmonary hypertension in a series of 131 patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2001;164:219-24.
  17. Oswald-Mammosser M, Weitzenblum E, Quoix E, Moser G, Chaouat A, Charpentier C, et al. Prognostic factors in COPD patients receiving long-term oxygen therapy. Chest.1995;107:1193-8.
  18. Fishman AP. State of the art: Chronic cor pulmonale. Am Rev Respir Dis.1976;114:775-94.

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