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ISSN: 2394-4137 (E) 2394-6318 (P)

IJIMS.2018.113

Type of Article: Original Research

Volume 5; Issue 5: 2018

Page No.: 635-639

DOI: 10.16965/ijims.2018.113

 

ISOLATION, IDENTIFICATION OF FUNGAL AGENT CAUSING KERATITIS, ANTIFUNGAL SENSITIVITY TESTING

Venkatalaxmi Rajamanickam *1, Aruna Sunder 2, Lingam Jaya Lakshmi 3.

*1 Assistant Professor in Microbiology, Dr. Patnam Mahender Reddy Institute of Medical sciences and hospital, Chevella, Rangareddy, Telangana, India.

2 Retd. Professor in Microbiology, Sarojini Devi eye hospital, Hyderabad, Telangana, India.

3 Associate professor in Microbiology, Osmania Medical College, Koti, Hyderabad, Telangana, India.

Corresponding Author: Dr. Venkatalaxmi Rajamanickam, Assistant Professor in Microbiology, Dr. Patnam Mahender Reddy Institute of Medical sciences and hospital, Chevella, Rangareddy, Telangana, India. E-Mail: drlaxmi04@gmail.com

Abstract:

The present study was carried out in the Department of Microbiology Sarojini Davi Eye Hospital, a tertiary care centre. Hyderabad, for a period of six months, with 150 clinically diagnosed keratitis cases were studied for microbial involvement. Incidence of keratitis was higher in males than females. Maximum incidence was found to be in the age group of 41-60 years. Maximum incidence was found in rural residents. Incidence of keratitis was higher in agricultural workers and labourers than in other occupations. Corneal trauma with vegetative matter was identified as the major predisposing factor followed by co-existing ocular conditions. 33 cases yielded pure fungal isolates and 24 cases were of mixed bacterial and fungal etiology. Culture sterile was 42 cases. Aspergillus species was the predominant fungal pathogen isolated followed by Fusarium species. Antifungal susceptibility showed highest sensitivity to Voriconazole followed by Amphotericin – B and Itraconazole.

Key words: Corneal trauma, Aspergillus, Amphotericin – B and Itraconazole.

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