IJIMS.2015.130

Type of Article: Case Report

Volume 2; Issue 10: October 2015

Page No.: 170-174

DOI: 10.16965/ijims.2015.130

 

Conjoined Twins (Thoraco-Omphalopagus)

Prasad Arun *1, Kapoor Kanchan 2, Sharma Anshu 3, Abraham Joseph 4.

*1 Department of Anatomy, Andaman Nicobar Islands Institute of Medical Sciences, Port Blair, India.

2,3,4 Department of Anatomy, Government Medical College, Chandigarh, India.

CORRESPONDING AUTHOR ADDRESS: Dr. Arun Prasad, Department of Anatomy, Andaman Nicobar Island Institute of Medical Sciences, Port Blair, Andaman Nicobar Islands, India.  E-Mail: drprasadarun@gmail.com

 

ABSTRACT

Conjoined twins are a rarely seen congenital anomaly with severe mortality. Among the different variety of conjoined twins, Thoraco-omphalopagus is the most common type, wherein the two foetuses are joined at thorax and upper abdomen region. In this type of twins usually there is single heart, but lungs will be separate. In GIT, the foregut will be separate, but midgut may be shared by both twins. Hindgut will be separate. The exact cause is unknown, but it is mostly considered to be an irregular division of the zygote. One such case was observed during routine foetal autopsy performed in Dept of Anatomy, GMCH-32, and Chandigarh. The mother was 21yrs old prime gravida and the condition was diagnosed at the time of USG examination at 13+6 weeks of gestational age. Autopsy was performed after taking full consent. The foetuses had single umbilical cord and sex of both the foetuses was male. After autopsy it was found that both foetuses shared single heart, stomach, small intestine, large intestine, liver and spleen. However there was development of separate lungs and organs of Genito-urinary system. There are two theory proposed for the formation of the conjoined twins. A fusion theory which is more accepted and other one is fission theory. The exact mechanism of formation of twins, obstetrical and surgical importance and other details will be discussed in detail with the available literature.

KEY WORDS: Conjoined Twins, Thoraco-ompahlopagus, Congenital Anomaly.

REFERENCES

  1. Birth Defects Registry of India A ‘Saving Babies’ Project. Available at: http://www.medindia.net/news/health watch/Birth Defects Registry of India A Saving Babies Project 78389 1. htm#ixzz2GtO6Ld5M.
  2. “Birth Defects” (http://www.cdc.gov/ncbddd/birthdefects/index.html). March 16, 2015. Retrieved 8 May 2015.
  3. GBD 2013 Mortality and Causes of Death, Collaborators (17 December 2014). “Global, regional, and national agesex specific allcause and causespecific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013.” (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340604). Lancet 385 (9963): 117–71.
  4. Gittelsohn A., Milham S. Statistical study of twins—methods. Am. J. Public Health Nations Health, 1964; 54;286–294.
  5. Fernando J., Arena P., Smith D. W. Sex liability to single structural defects. Am. J. Dis. Child;1978;132:970–972.
  6. Lubinsky M. S. Classifying sex biased congenital anomalies. Am. J. Med. Genet.1997:69:225–228.
  7. Lary J. M., Paulozzi L. J. Sex differences in the prevalence of human birth defects: a populationbased study. Teratology.2001:64:237–251.
  8. Wei Cui, ChangXing Ma, Yiwei Tang, e. a. Sex Differences in Birth Defects: A Study of OppositeSex Twins. Birth Defects Research (Part A).2005:73:876–880.
  9. Kumar, Abbas and Fausto, eds., Robbins and Cotran’s Pathologic Basis of Disease, 7th edition, p.470.
  10. Dicke JM. “Teratology: principles and practice”. Med. Clin. North Am. 1989:3 (3): 567-82.
  11. Sangari, S.K., Khatri, K., Pradhan, S. Omphalopagus Ischiopagus Tetrapus Conjoined Twins — A Case Report. J Anat. Soc. India,2001:50(1);40-42.
  12. Amar Taksande, Krishna Vilhekar, Pushpa Chaturvedi, et al. Congenital malformations at birth in Central India: A rural medical college hospital based data. Indian J Hum Genet. 2010:3: 159–163.
  13. Mathur BC, Karan S, Vijaya Devi KK.Congenital malformations in the newborn.Indian Pediatr. 1975:12:179-83.
  14. Mohanty C, Mishra OP, Das BK, Bhatia BD, Singh G, et al. Congenital malformation in newborn: A study of 10,874 consecutive births. J Anat Soc India. 1989; 38:101–11.
  15. Suguna Bai NS, Mascarene M, et al. An etiological study of congenital malformation in the newborn. Indian Pediatr. 1982 Dec; 19:1003-7.
  16. Dutta V, Chaturvedi P, et al. Congenitalmalformations in rural Maharashtra. Indian Pediatr. 2000;37:998-1001.
  17. Ordóñez MP, Nazer J, Aguila A, Cifuentes, et al. Congenitalmalformations and chronic diseases of the mother. Latin American Collaborative Study of CongenitalMalformations (ECLAMC) 1971-1999. LRev Med Chil 2003;131:404-11.
  18. New Delhi: Reproductive health; Annualreport 2002-03. Indian Council of Medical Research; p. 91.
  19. O’Dowd MJ, Connolly K, Ryan A, et al. Neural tube defects in rural Ireland. Arch D is Child. 1987 Mar; 62(3):297-8.
  20. Benacerraf B, Barss V, Laboda L. A sonographic sign for the detection in the second trimester of the fetus with Down’s syndrome. Am J Obstet Gynecol. 1985;151:1078–1079.
  21. Snijders RJM, Nicolaides KH. In: Ultrasound markers for fetal chromosome defects. Canforth, UK: Parthenon Publishing; 1996. Assessment of risks; pp. 63–120.

 

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