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ISSN: 2394-4137 (E) 2394-6318 (P)

IJIMS.2016.105

Type of Article: Original Research

Volume 3; Issue 3: March 2016

Page No.: 238-241

DOI: 10.16965/ijims.2016.105

 

Overlaps of CA-125 Bio Marker As a kind of Medical Error in Women’s Complications: A Cross Sectional Study in Korramabad (west of Iran)

Seyyed Amir Yasin Ahmadi 1, Afshin Hasanvand 1, Parastoo Baharvand *2, Asghar Aaliehpour 3.

1 Student Research Committee, Lorestan University of Medical Sciences­, Khorramabad, Iran.

*2 Department of Social Medicine, Lorestan University of Medical Sciences­, Khorramabad, Iran.

3 Department of Pathology, Lorestan University of Medical Sciences­, Khorramabad, Iran.

CORRESPONDING AUTHOR ADDRESS: Dr. Parastoo Baharvand, Department of Social Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran. E-Mail: dr.baharvand@gmail.com­­

ABSTRACT

Introduction: Medical errors secondary to false positive and false negative of immunoassay have not ever been as considerable as therapeutic and surgical errors so. Of the overlapping bio markers, Cancerous Antigen 125 (CA-125) can be noted as a factor which its level is high in a wide spectrum of disease that mainly leads to medical error between endometriosis and ovarian cancer. So we intend to represent a way to distinguish endometriosis from the other CA-125 related complications.

Materials and Methods: Present paper is a cross sectional study on the medical records of Noor pathobiology laboratory in Khorramabad (west of Iran) during 2014-2015.

Results: There were totally 693 records for CA-125. In 90 patients (about 12.9%) the level of CA-125 was high that 7 individuals were male. Totally, CA-125 level was high in about 10% and 13% of respectively male and female required to the test patients. Among the female patients having high level of CA-125, only 20 of them were required to test Carcino-embryonic Antigen (CEA). No one of these 20 individuals has abnormal CEA.

Conclusion: It can be concluded that dual assaying CA-125 and CEA might be a helpful method to distinguish endometriosis from ovarian cancer. Also it is suggested to use combined method including immunoassay and imaging. Further research is necessary to identify a more specific bio marker for endometriosis and other complications.

Key words: medical errors, CA-125, CEA, endometriosis, ovarian cancer.

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