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ISSN: 2394-4137 (E) 2394-6318 (P)

IJIMS.2017.112

Type of Article: Original Research

Volume 4; Issue 6: 2017

Page No.: 507-511

DOI: 10.16965/ijims.2017.112

 

PRIMARY TUMORS AND TUMOR-LIKE LESIONS OF BONE IN CHILDREN

George Mathew *1, Shwetha Jose 2.

*1 Assistant professor, Department of Orthopaedics, MOSC medical college, Kolenchery, Ernakulam, Kerala, India.

2 Assistant professor, Department of Pathology, Sree Narayana Institute of Medical Sciences, Chalakka, North Paravur, India.

Corresponding Author: Dr. George Mathew, Assistant professor, Department of Orthopaedics, MOSC medical college, Kolenchery, Ernakulam, Kerala, India.

Contact number: +919539778679 E-Mail:

Abstract:

Objective: The aim of this study was to evaluate the characteristics of bone tumors in pediatric population at the Department of Orthopedics at Sree Narayana Institute of Medical sciences, Chalakka, North Paravur during the period from March 2014 to January 2017.

Materials and Methods: This study was carried out at our Medical teaching hospital from March 2014 to January 2017. A total of 50 cases were included in the study. All the patients included were below 18 years of age. Most of the patients were referred to orthopedic department from pediatric department. All the patients underwent complete radiological and routine investigations and biopsy was taken to confirm the diagnosis.

Results: Of the 50 cases, 38 (76%) were male and 12 (24%) were female. The mean age of all cases was 13 years (range: 1-18 years).

Out of 50 patients, 34 cases (68%) were benign, 3 cases (6%) were malignant and 13 (26%) were tumor like lesions. Out of benign tumors, most common was the Osteochondroma (52%) followed by osteoid osteoma (16%).3 cases of malignant tumors were found in present study in which 2 cases (4%) were of chondrosarcoma and 1 case (2%) of Ewing’s Sarcoma.Fibrous dysplasia, Non-ossifying fibromas, Simple bone cysts and aneurismal bone cysts, were found in 5 (10%), 3 (6%), 3 (6%), and 2 (4%) of the patients with tumor-like lesions, respectively.

Conclusion: data from our series showed both similarities and differences with the literature. We suggest the formation of larger series to achieve better results and beneficial information in regard to distribution of bone and soft tissue tumors in our country, thereby benefitting both pediatric and public health.

Key words: Pediatric Bone Tumor, Benign Tumor, Malignant Tumor.

REFERENCES

  1. Gülman B, Dabak N, Yöndem F. Samsun İli Hastanelerinde kemik tümörü tanısı konulan 140.
  2. olgunun incelenmesi. Türkiye Klinikleri Tıp Bilimleri Araştırma Dergisi 1988; 6: 153-159.
  3. Kösem M, Bayram I. Distribution and evaluation of extremity, bone and soft tissue tumors in Van region. Van Med J 2001; 8:93-96.
  4. Solakoğlu D, Benzer E. Distribution of bone tumors according to age, sex and tumor site. Acta Ongologica Turcica 2005;38:38-43.
  5. Güngör Ş. Demographic features of childhood benign bone tumors and evaluation of clinical approach. Acta Ongologica Turcica 2008;41:7-13.
  6. Yücetürk G, Sabah D, Kececi B, Kara AD, Yalcinkaya S. The distribution of bone and soft tissue tumors. Acta Orthop Traumatol Turc 2011;45:135-143.
  7. Enneking WF. Musculoskeletal tumor surgery. 1st edition. New York, NY: Churchill Livingstone; 1983.
  8. Pettersson H, Springfield DS, Enneking WF. Radiologic management of musculoskeletal tumors. Philadelphia: Springer publishers; 1999.
  9. Enneking WF, Spanier SS, Goodman MA. A system for the surgical staging of musculoskeletal sarcoma. Clin Orthop. 1980;153:106.
  10. Aboulafia AJ, Kennon RE, Jelinek JS. Benign bone tumors of childhood. J Am Acad Orthop Surg. 1999;7:377–388.
  11. Gurney J, Swensen A, Bulterys M. Malignant bone tumors. Cancer Incidence and Survival among Children and Adolescents: United States SEER Program 1975-1995. In: Ries L, Smith MA, Gurney JG, Linet M, Tamra T, Young JL, editors. Bunin GR National Cancer Institute: SEER Program. 1999;99–110.
  12. Arndt CA, Rose PS, Folpe AL, Laack NN. Common musculoskeletal tumors of childhood and adolescence. Mayo Clin Proc 2012;87:475-487.
  13. Arndt CA, Crist WM. Common musculoskeletal tumors of childhood and adolescence. N Engl J Med 1999;341:342-352.
  14. Karakurt L, Yılmaz E, Varol T, Özdemir H. Dirsekte soliter enkonroma bağlı gelişen ulnar sinir basısı: olgu sunumu. Acta Orthop Traumatol Turc 2004;38:291-294.
  15. Gebhart MC, Ready JE, Mankin HJ. Tumors about the knee in children. Clin Orthop Relat Res 1990;255:86-110.
  16. Smith MA, Ries LAG. In: Chidhood cancer: Incıdence, survival, and mortality in Principles and Practice of Pediatric Oncology. 4th edition. Pizzo PA, Poplack DG, editors. Philadelphia: Lippincott Williams and Wilkins; 2002. pp. 1–12.
  17. Caudill JS, Arndt CA. Diagnosis and management of bone malignancy in adolescence. Adolesc Med State Art Rev. 2007;18:62–78.
  18. Kısmet E, Köseoğlu V. Bone tumors in childhood. Turkiye Klinikleri J Pediatr-Special Topics. 2004;2:899–903.
  19. Van den Berg H, Kroon HM, Slaar A, Hogendoorn P. Incidence of biopsy-proven bone tumors in children: a report based on the Dutch pathology registration “PALGA” J Pediatr Orthop. 2008;28:29–35.
  20. Obalum DC, Giwa SO, Banjo AF, Akinsulire AT. Primary bone tumours in a tertiary hospital in Nigeria: 25 year review. Niger J Clin Pract. 2009;12:169–172.
  21. Senac MO Jr, Isaacs H, Gwinn JL. Primary lesions of bone in the 1st decade of life: retrospective survey of biopsy results. Radiology. 1986;160:491–495.
  22. Lasebikan OA, Nwadinigwe CU, Onyegbule EC. Pattern of bone tumours seen in a regional orthopaedic hospital in Nigeria. Niger J Med. 2014;23:46–50.
  23. Mohammed A, Isa HA. Pattern of primary tumours and tumour-like lesions of bone in Zaria, northern Nigeria: a review of 127 cases. West Afr J Med. 2007;26:37–41.
  24. Obalum DC, Eyesan SU, Ogo CN, Enweluzo GO. Multicentre study of bone tumours. Niger Postgrad Med J. 2010;17:23–26.
  25. Abdulkareem FB, Eyesan SU, Akinde OR, Ezembakwe ME, Nnodu OE. Pathological study of bone tumours at the National Orthopaedic Hospital, Lagos, Nigeria. West Afr J Med. 2007;26:306–311.
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