IJIMS.2018.116

Type of Article: Original Research

Volume 5; Issue 6: 2018

Page No.: 650-654

DOI: 10.16965/ijims.2018.116

 

CONSIDERATION OF THYROID DYSFUNCTION FOR MENSTRUAL ABNORMALITIES IN PREMENOPAUSAL WOMEN

Anita Ramesh Annaldasula 1, Shivakrishna Gouroju *2.

1 Associate professor, obstetrics & Gynecology, Shanthiram Medical College, Nandyal, Kurnool, Andhra Pradesh, India.

2 Tutor in Biochemistry, Andaman and Nicobar Island Institute of Medical sciences, Port Blair, India.

Corresponding author: Dr. Shivakrishna Gouroju, Tutor in Biochemistry, Andaman and Nicobar Island Institute of Medical sciences, Port Blair, India.

E-Mail: skgouroju@gmail.com

Abstract:

Abnormal Uterine Bleeding (AUB) is one of the most frequently encountered conditions in women, it has been recognized that thyroid dysfunction may have profound effects on the female reproductive system, menstrual disturbances and cause of excessive puberty bleeding.  Hence this study is to evaluate the thyroid function in patients having abnormal uterine bleeding from age group of 20 to 40 yrs with 100 AUB patients which will help in further management and also know the prevalence of thyroid disorders in abnormal uterine bleeding. Out of 100 patients 42 women with thyroid abnormality, heavy menstrual bleeding was seen in 21 (50%) women, 11 (26.19%) had Polymenorrhagia, 10 (23.81%) had Oligomenorrhoea, in women with hypothyroidism (30 women) was heavy menstrual bleeding in 17 (56.67%) women, 6 (20%) had Oligomenorrhoea, 7 (23%) had Polymenorrhagia, and in 18 women with hyperthyroidism, 10 (55.56%) had heavy menstrual bleeding, 4 (22.22%) had oligomenorrhoea, 4 (22.22%) had Polymenorrhagia. So that clinicians should consider that thyroid dysfunction is as an important associated factor for menstrual abnormalities even in premenopausal women. It is important to screen all women for thyroid abnormality who are presenting with AUB especially with non-structural causes of AUB. Correction of thyroid abnormalities also relieves AUB. This will avoid unnecessary hormonal treatment and surgery.

Key words: Abnormal Uterine Bleeding, thyroid dysfunction, heavy menstrual bleeding, Oligomenorrhoea, Polymenorrhagia.

REFERENCES

  1. Berek JS, Adarshi EY and Hillard PA. In endocrine disorders. Novaks Gynaecology, 12th William & Wilkins, Gopson paper Ltd., Noida. 2001; pp.864.
  2. Rebecca Abraham, V Srinivasa Murugan Et al., :Thyroid disorders in women of Puducherry, Indian journal of clinical biochemistry.2009:24:52-9.
  3. Danese MD, Powe NR, Swain CT, Ladenson PW. Screening for mild thyroid failure at the periodic health examination. A decision and Cost effective analysis. JAMA 1996; 276: 285.
  4. John W. Ely M.D.,MSPH, Colleen M. Kennedy, MD, MS, Elizabeth C. Clark, MD et al.,:Abnormal uterine bleeding: A management algorithm. Department of Obstetrics and Gynaecology, University of Iowa Carver College of Medicine, Lowa Cirty.IA, Pg. 1-17.
  5. Joschi JV, Bhandarkar SD, Chadha M, Balaiah D, Shah R. Menstrual irregularities and lactation failure may precede thyroid  dysfunction on goiter. J Postgrad Med 1993; 39(3): 137-41.
  6. Wilansky DL, Griesman B. Early hypothyroidism in patients with menorrhagia. Am J Obstet Gynaecol. 1989; 160:673-7.
  7. Jayadey Mukherjee and NN Roy Chowdhary.A review  of 70 cases of puberty menorrhagia. J Obst and Gynaec of India. 1986 pp.121.
  8. Pushpa S, BikhaRam D, Razia MA, ZulfiquarAli SS, Tarachand D, Ishrat B. Impaired thyroid functions in patients with menstrual disturbances (An experience of a private clinic). World Appl Sci J. 2009;7(4):538-42.
  9. Sruthi T, Shilpa SB, Gopal N. Prevalence of hypothyroidism in patients with provisional diagnosis of DUB. J Evol Med Dent Sci. 2014;3(11):2967-72.
  10. Sharma N, Sharma A. Thyroid profile in menstrual disorders. JK Sci. 2012;14(1):14-7.
  11. Padmaleela K, Vimala T, Lavanya KM, Kiranmai D. Thyroid disordrs and dysfunctional uterine bleeding (DUB) among reproductive age group women. A cross sectional study in a tertiary care hospital in Andhra Pradesh, India. Int J Med Pharm Sci. 2013;4(1):41-6.
  12. Byna P, Siddula S, Kolli S, Shaik MV. Thyroid abnormality in perimenopausal women with abnormal uterine bleeding. Int J Res Med Sci 2015;3:3250-3.
  13. Dipak Lahiri, Anian Dasgupta, Sarmila Kundu. Menstrual pattern and fertility status of hypothyroid women. J Obst and Gynaec of India 1996; 47: 663.
  14. Bhavani N, Avanthi S, Aradhana G, Sangeeta C, Prasannakumar VS. A study of correlation between abnormal uterine bleeding and thyroid dysfunction. Int J Recent Trends in Sci Technol. 2015;14(1):131-5.
  15. Gowri M, Radhika BH, Harshini V, Ramaiaha R. Role of thyroid function tests in women with abnormal uterine bleeding. Int J Reprod Contracept Obstet Gynecol. 2014;3(1):54-7.

Download Full Text TOC