IJIMS.2018.124

Type of Article: Original Research

Volume 5; Issue 7: 2018

Page No.: 687-692

DOI: 10.16965/ijims.2018.124

CLINICAL PROFILE OF LINEAR DERMATOSES EMPHASIZING ON THEIR PRESENTATION ALONG THE BLASHCO’S LINES

N. Ramanjanamma 1, Garnipudi Pavani *2, Jasmine D 2.

1 Venereology, Associate professor of Dermatology, Viswabharathi Medical College, Kurnool.
2 Assistant professor of DVL, Viswabharathi Medical College, Kurnool.

Corresponding author: Dr. Garnipudi Pavani, Assistant professor of DVL, Viswabharathi Medical College, Kurnool, Andhra Pradesh, India.
E-Mail: pavanigarnipudi@gmail.com

Abstract:

Introduction: Skin lesions present with innumerable patterns like Discoid, Petaloid, Arcuate, Annular, Polycyclic, Livedo, Reticulate, Target, Stellate, Digitate, Linear, Serpiginous and Whorled. Most of the linear lesions follow the Blaschko’s lines. In this study the incidence of linear dermatoses, the age and sex incidence, various types of clinical presentation among the patients, the association, and various sites of distribution and clinic histopathological correlation of various linear dermatoses.

Materials and Methods: A Descriptive study of patients with linear dermatoses attending the Outpatient Department of Viswabharathi Medical College, Kurnool, from January 2017 to December 2017. Detailed history including family history, Marital Status, History of trauma documented with clinical examination. After counselling and after recording their consent for the test, skin biopsy done along with routine investigations and the results are evaluated. Results: Among the 90 cases, Lichen striatus was the most common presentation followed by linear epidermal naevus and Linear Lichen planus in our study. Family history of similar leisions in any of these patients. Out of 90 cases, 83 cases showed unilateral distribution and only the remaining 7 showed bilateral distribution of lesions in a linear pattern. 66 cases, had lesions mainly over the extremities, corresponding to the lines of Blaschko.

Conclusion: The Incidence of Linear Dermatoses during the period of January 2017 to December 2017 was 0.2 % Lichen striatus was founded more common, female preponderance. Majority of patients showed unilateral distribution more on the extremities. Histopathological correlation shows the importance of histopathology which ultimately changing the management in any given condition. Very few associations were noted.

Key words:  Linear Dermatoses, lines of Blaschko, skin biopsy, Lichen striatus, and Distribution of lesions in a linear pattern.

REFERENCES

  1. Soma Y, Fujimoto M. Frontoparietal scleroderma (en coup de sabre) following Blaschko’s lines. J Am Acad Dermatol 1998; 38: 366-8.
  2. Montgomery DW. The cause of the streaks in nevus linearis. J Cutan Genitourinary Dis 1901; 19: 455–64.
  3. Moss C. Cytogenetic and molecular evidence for cutaneous mosaicism:The Ectodermal origin of Blaschko lines. Am J Med Genet 1999; 85: 330–3.
  4. Jackson R. The lines of Blaschko: a review and reconsideration. Br J Dermatol 1976; 95: 349-60.
  5. Huh W,Fujiwara K et al. Congenital acantholytic dyskeratotic epidermal nevus following Blaschko’s lines versus segmental Darier’s disease. Eur J Dermatol. 2007 ;17(2) :130-2.
  6. Lichen Striatus: Clinical features and follow up in 12 patients. Hauber K, Rose C, Brocker EB, Hamm H. European Journal of Dermatology 2000, Oct-Nov; 10(7): 536-9.
  7. Boyd AS, Neldner KH. Lichen planus. J Am AcadDermatol 1991; 25:593-619.
  8. LEVER’S Histopathology of skin –David E. Elder -10th edition. Page no. 185-91.
  9. Rook’s Textbook of Dermatology-Tony Burns/ Stephen Breathnach, 8th Edition Vol 1;18.4 -18.5, 51-70.

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