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ISSN: 2394-4137 (E) 2394-6318 (P)

IJIMS.2018.127

Type of Article: Original Research

Volume 5; Issue 7: 2018

Page No.: 705-708

DOI: 10.16965/ijims.2018.127

FACTORS DETERMINING OUTCOMES IN ACUTE EXACERBATIONS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE

G. Peter Praveen Herald, Suresh Kumar Cherlopalli *.

MD Pulmonary Medicine, Assistant Professor in Viswabharathi Medical College, Penchikalapadu, Kurnool, Andhra Prasesh, India. 

Corresponding author: Dr. Suresh Kumar Cherlopalli, MD Pulmonary Medicine, Assistant Professor in Viswabharathi Medical College, Penchikalapadu, Kurnool, Andhra Prasesh, India. E-Mail: septasure@gmail.com

Abstract:

Background: factors determining outcomes in acute exacerbations of chronic obstructive pulmonary disease (AECOPD) would help us to understand the incidence of acute exacerbation of COPD in the Rayalasema community of patients and the type of bacterial infections in acute exacerbations of chronic obstructive pulmonary disease in the cases admitted to Viswabharathi Medical College Hospital, Kurnool.

Subjects and Methods: 100 patients (72 males, 28 females) aged between 45 and 85 years were included in the study. A detail history was elicited and complete examination was done. The sputum specimen was collected using sterile sputum cups and subjected to Gram’s stain, culture and biochemical reactions.

Results: Our study shows 47 positive sputum cultures out of total 100 cases. Out of 100 cases 72% were males and 28% were females. The predominant clinical feature observed in our study was cough with expectoration, exertional dyspnoea and production of mucopurulent sputum. The prevalence of Gram negative bacteria was 55% and a Gram positive bacterium was 45%. Klebsiella pneumoniae was the commonest bacteria isolated (38%) followed by Staphylococcus aureus (18%).

Conclusions: In a developing country like India AECOPD is more common in adults more than 55 years of age due to smoking habits and high indoor pollution. This leads to a major impact on the quality of life of patients with the condition. They are a major cause of hospital admission and health care utilization.

Key words: Acute Exacerbation of COPD, Sputum Cultures, Klebsiella pneumoniae, and Staphylococcus aureus.

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